A2aR/A2bR antagonist-1 是一种口服生物利用的选择性的双腺苷受体 (A2aR/A2bR) 拮抗剂,具有免疫调节活性。
货号:ajcx14320
CAS:2239273-34-6
分子式:C23H22N8O
分子量:426.47
溶解度:DMSO: 250 mg/mL (586.21 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
A2aR/A2bR antagonist-1 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist with immunomodulatory activity[1].
[1]. Seitz L, et al. Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers. Invest New Drugs. 2019 Aug;37(4):711-721.