MS4322 (YS43-22) 是一种 PRMT5 的降解剂,也是探索 PRMT5 在健康和疾病中功能的有价值的化学工具 (PROTAC)。
货号:ajcx38818
CAS:2375432-47-4
分子式:C55H76N10O12S
分子量:1101.32
溶解度:DMSO : 100 mg/mL (90.80 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease.
[1]. Shen Y, et al. Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. J Med Chem. 2020 Sep 10;63(17):9977-9989.