Bromo-PEG2-bromide 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。
货号:ajcx35950
CAS:31255-10-4
分子式:C6H12Br2O2
分子量:275.97
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Chen TH, et al. Metal-organic frameworks constructed from crown ether-based 1,4-benzenedicarboxylic acid derivatives. Dalton Trans. 2016 Feb 21;45(7):3063-9.