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Pyridoxal 5&rsquo-phosphate monohydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pyridoxal 5&rsquo-phosphate monohydrate图片
规格:98%
分子量:265.16
包装与价格:
包装价格(元)
1g电议
5g电议

产品介绍
Pyridoxal 5’-phosphate hydrate 是维生素 B6 的活性形式,它是多种酶 (包括可催化神经递质多巴胺和5-羟色胺生产的最后阶段的芳族 L-氨基酸脱羧酶) 的重要辅因子。Pyridoxal 5’-phosphate hydrate 是维生素 B6 在细胞内磷酸化过程中最重要的辅酶变异体,可与其他变异体互换,包括 PNP 和 PMP。
货号:ajcx35134
CAS:41468-25-1
分子式:C8H12NO7P
分子量:265.16
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Pyridoxal 5’-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5’-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2].

[1]. Allen GF, et al. Pyridoxal 5’-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.J Neurochem. 2010 Jul;114(1):87-96.
[2]. CalderÓn-Ospina CA, et al. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.CNS Neurosci Ther. 2020 Jan;26(1):5-13.