QCA570 is an highly potent and efficacious BET degrader based on PROTAC, with an IC₅₀ of 10 nM for BRD4 BD1 Protein. QCA570 achieves complete and durable tumor regression in leukemia xenograft models in mice at well-tolerated dose-schedules. QCA570 is the most potent and efficacious BET degrader reported to date.

纯度：≥98%

CAS：2207569-08-0