CBP/p300 ligand 2 是 dCBP-1 的 PROTAC 靶蛋白的配体。dCBP-1 是一种有效且选择性的 p300/CBP 异双功能降解剂。
货号:ajcx34052
CAS:2484741-78-6
分子式:C27H34F2N8O
分子量：524.61
溶解度:DMSO : 200 mg/mL (381.24 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

CBP/p300 ligand 2 (example 229) has no toxicity to LNCaP prostate cancer cells[1].

[1]. Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. O2020173440A1.