(R)-MLN-4760 是 MLN-4760 的活性较低的 R 型异构体,是一种 ACE2 抑制剂,IC50 值为 8.4 µM。
货号:ajcx32588
CAS:305335-29-9
分子式:C19H23Cl2N3O4
分子量:428.31
溶解度:DMSO : 14.29 mg/mL (33.36 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 µM. (R)-MLN-4760 is the less active isomer[1].
(R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760[1].
参考文献:
[1]. Dales NA, et, al. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J Am Chem Soc. 2002 Oct 9;124(40):11852-3.