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EGNHS
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
EGNHS图片
包装:100mg
规格:98%
市场价:712元
分子量:456.36

产品介绍
EGNHS是一种PROTAClinker,属于alkyl/ether类。可用于合成PROTAC分子。
货号:ajcx32466
CAS:70539-42-3
分子式:C18H20N2O12
分子量:456.36
溶解度:DMSO: 100 mg/mL (219.13 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562