您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 2,6-Dimethylquinoline
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
2,6-Dimethylquinoline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2,6-Dimethylquinoline图片
包装:500mg
规格:98%
市场价:445元
分子量:157.22

产品介绍
2,6-Dimethylquinoline是一种来自Peucedantupraeruptorum根的天然成分,是CYP1A2的抑制剂,IC50为3.3µM。2,6-Dimethylquinoline也抑制CYP2B6的活性,IC50为480µM。
货号:ajcx32326
CAS:877-43-0
分子式:C11H11N
分子量:157.22
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 µM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 µM[1][2][3].


[1]. Laura E Korhonen, et al. Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. J Med Chem. 2005 Jun 2;48(11):3808-15. [2]. L E Korhonen, et al. New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis. Br J Pharmacol. 2007 Apr;150(7):932-42. [3]. Cun Zhang, et al. Studies on chemical constituents from roots of Peucedanum praeruptorum II. Zhongguo Zhong Yao Za Zhi. 2006 Aug;31(16):1333-5.