6-Methyluracil(Pseudothymine)，一种尿嘧啶的代谢产物，可用作乙酰乙酰辅酶A(AACoA)积累的指标。6-Methyluracil在体内具有抗辐射作用。
货号:ajcx32274
CAS:626-48-2
分子式:C5H6N2O2
分子量：126.11
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo[1][2].

6-Methyluracil (50 mg/kg; a single i.p.) produces a pronounced radioprotective effect in BALB and SHK mice[2].

[1]. Cromby CH, et, al. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. J Inherit Metab Dis. 1994;17(1):81-4. [2]. Taran IP, et, al. [The antiradiation action of 6-methyluracil]. Radiobiologiia. Mar-Apr 1993;33(2):285-90.