KB02-COOH是泛素E3连接酶配体KB02的合成片段。KB02可用于PROTAC的合成,例如KB02-JQ1和KB02-SLF。
货号:ajcx30866
CAS:2375196-30-6
分子式:C13H14ClNO4
分子量:283.71
溶解度:DMSO: 66.67 mg/mL (234.99 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 and KB02-SLF [1].
[1]. Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.