JTP10-△-R9TFA是选择性的JNK2多肽抑制剂,其IC50值为89nM,对JNK2的选择性是JNK1和JNK3的10倍以上。
货号:ajcx30862
CAS:N/A
分子式:C119H214F3N53O26
分子量:2860.31
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
JTP10-△-R9 TFA is a selective JNK2 peptide inhibitor, with an IC50 of 89 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3[1].
JTP10-△-R9 TFA inhibits the migration of PyVMTjnk2+/+ cells and PyVMTjnk2-/- cells expressing GFP-JNK2α[1].
[1]. Tamer S. Kao, et al. Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. ACS Chem Biol. 2011 Jun 17;6(6):658-66.