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BIO-11006 acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BIO-11006 acetate图片
规格:98%
分子量:1110.22
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
BIO-11006acetate,MANS肽的类似物,是一种MARCKS(myristoylatedalanine-richCkinasesubstrate)抑制剂。
货号:ajcx30278
CAS:N/A
分子式:C48H79N13O17
分子量:1110.22
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

BIO-11006 acetate, an analog of the MANS peptide, is a MARCKS (myristoylated alanine-rich C kinase substrate) inhibitor[1].


Inhaled, aerosolized BIO-11006 acetate attenuates LPS-induced neutrophil influx into the lung, activation of NF-κB, and expression of the proinflammatory cytokines, KC and TNF-α, and thus reverses the development of lung injury in mice instilled intratracheally with LPS[1].

[1]. Yin Q, et al. An Inhaled Inhibitor of Myristoylated Alanine-Rich C Kinase Substrate Reverses LPS-Induced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2016 Nov;55(5):617-622.