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Rivaroxaban D4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rivaroxaban D4图片
规格:98%
分子量:439.91
包装与价格:
包装价格(元)
10mg电议
25mg电议

产品介绍
Rivaroxaban D4 (BAY 59-7939 D4) 是 Rivaroxaban 的氘代物。Rivaroxaban 是一种高效,选择性凝血因子 Xa (FXa) 抑制剂,IC50 为 0.7 nM,Ki 为 0.4 nM。
货号:ajcx29662
CAS:1132681-38-9
分子式:C19H14D4ClN3O5S
分子量:439.91
溶解度:DMSO: Soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Rivaroxaban D4 (BAY 59-7939 D4) is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM)[1][2].


[1]. Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19) [2]. Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3(3):514-21.