您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Trifluoperazine N-Glucuronide
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Trifluoperazine N-Glucuronide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Trifluoperazine N-Glucuronide图片
规格:98%
分子量:583.6
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
Trifluoperazine N-Glucuronide (UGT1A4) 作为人类 UGT1A 亚型之一,在肝脏中表达。
货号:ajcx25402
CAS:165602-90-4
分子式:C27H32F3N3O6S
分子量:583.6
溶解度:Methanol: soluble,Water: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Trifluoperazine N-glucuronide is a metabolite of the antipsychotic agent trifluoperazine .1,2It is formed from trifluoperazine by the UDP-glucuronosyltransferase (UGT) isoform UGT1A4.2


1.Luo, H., Hawes, E.M., McKay, G., et al.N(+)-glucuronidation of aliphatic tertiary amines in human: antidepressant versus antipsychotic drugsXenobiotica25(3)291-301(1995) 2.Fujiwara, R., Nakajima, M., Yamanaka, H., et al.Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activitiesDrug Metab. Dispos.35(10)1781-1787(2007)