规格: | 98% |
分子量: | 363.7 |
包装 | 价格(元) |
500ug | 电议 |
1mg | 电议 |
5mg | 电议 |
Background:
Triclabendazole-13C-d3is intended for use as an internal standard for the quantification of triclabendazole by GC- or LC-MS. Triclabendazole is a benzimidazole anthelmintic.1It eliminates both immature and adult flukes in a sheep model ofF. hepaticainfection when administered at a dose of 10 mg/kg.2Triclabendazole (5 µM) also protects against glucose- or α-synuclein-induced apoptosis inS. cerevisiae viainhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.3
1.Shrifi, Y., Farahnak, A., Golestani, A., et al.Triclabendazole effect on protease enzyme activity in the excretory- secretory products of Fasciola hepatica in vitroIran. J. Parasitol.9(1)107-113(2014) 2.Smeal, M.G., and Hall, C.A.The activity of triclabendazole against immature and adult Fasciola hepatica infections in sheepAust. Vet. J.60(11)329-331(1983) 3.Lee, Y.J., Burlet, E., Wang, S., et al.Triclabendazole protects yeast and mammalian cells from oxidative stress: Identification of a potential neuroprotective compoundBiochem. Biophys. Res. Commun.414(1)205-208(2011)