规格: | 98% |
分子量: | 313.3 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Background:
Melicopine is an acridone alkaloid that has been found inZ. simulansand has antimalarial and anticancer activities.1It is active against the chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains ofP. falciparumwith IC50values of 29.7 and 33.7 µg/ml, respectively. Melicopine is cytotoxic to PC-3M and LNCaP prostate cancer, but not non-cancerous HEK293, cells (IC50s = 47.9, 37.8, and >100 µg/ml, respectively).
1.Wang, C., Wan, J., Mei, Z., et al.Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans HancePharmacogn. Mag.10(37)73-76(2014)