A polyketide with antibacterial and anticancer activities
货号:ajcx24466
CAS:274913-71-2
分子式:C20H16O6
分子量:352.3
溶解度:
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Rubiginone D2is a polyketide that has been found inStreptomycesthat has antibacterial and anticancer activities.1It is active againstS. aureusandE. coli, but notB. subtilis, in agar diffusion assays when used at a concentration of 64 µg/disc. Rubiginone D2inhibits growth of HM02, KATO III, HepG2, and MCF-7 cancer cells (GI50s = 0.1, 0.7,<0.1, and 7.5 µmol/L).
1.Puder, C., and Zeeck, A.New biologically active rubiginones from Streptomyces spJ. Antibiot. (Tokyo)53(4)329-336(2000)