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Prasugrel-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Prasugrel-d5图片
包装:1mg
规格:98%
市场价:4074元
分子量:378.5

产品介绍
普拉格雷-d5 是氘标记的普拉格雷。
货号:ajcx23290
CAS:1127252-92-9
分子式:C20H15D5FNO3S
分子量:378.5
溶解度:Chloroform: slightly soluble,Methanol: slightly soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Prasugrel-d5is intended for use as an internal standard for the quantification of prasugrel by GC- or LC-MS. Prasugrel is a prodrug form of the platelet purinergic P2Y12receptor antagonist R-99224.1Prasugrel (0.3 and 3 mg/kg) inhibitsex vivowashed platelet aggregation in rat platelet rich-plasma.2In vivo, prasugrel prevents thrombus formation (ED50= 0.68 mg/kg) and increases tail bleeding time in rats. Formulations containing prasugrel have been used in the prevention of blood clots.


1.Sugidachi, A., Asai, F., Yoneda, K., et al.Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type Gi-linked P2T antagonist, CS-747Br. J. Pharmacol.132(1)47-54(2001) 2.Sugidachi, A., Asai, F., Ogawa, T., et al.The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist propertiesBr. J. Pharmacol.129(7)1439-1446(2000)