A caged neurotransmitter used with photolysis
货号:ajcx22980
CAS:2226362-29-2
分子式:C14H17N3O6.CF3COOH
分子量：437.3
溶解度:Ethanol: 0.25 mg/mL,PBS (pH 7.2): 5 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations).¹Upon exposure to light (300 - 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds.¹This compound can be used to investigate the mechanisms of fast synaptic glutamate receptorsin situ.

1.Canepari, M., Nelson, L., Papageorgiou, G., et al.Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmittersJ.Neurosci.Methods112(1)29-42(2001)