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(±)11(12)-DiHET-d11
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(±)11(12)-DiHET-d11图片
规格:98%
分子量:349.6
包装与价格:
包装价格(元)
25ug电议
50ug电议
100ug电议
250ug电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx20820
CAS:N/A
分子式:C20H23D11O4
分子量:349.6
溶解度:DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

(±)11(12)-DiHET-d11contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)11(12)-DiHET by GC-or LC-mass spectrometry. Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity.1(±)11(12)-DiHET relaxes U-46619 -contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET .2


1.Oliw, E.H., Guengerich, F.P., and Oates, J.A.Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediatesJ. Biol. Chem.257(7)3771-3781(1982) 2.Fang, X., Kaduce, T.L., Weintraub, N.L., et al.Functional implications of a newly characterized pathway of 11,12-epoxyeicosatrienoic acid metabolism in arterial smooth muscleCirculation Research79784-793(1996)