C22H24O5
货号:ajcx19526
CAS:2361529-46-4
分子式:C22H24O5
分子量：368.4
溶解度:DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MGR1 is a probe that generates reactive oxygen species (ROS).1 Upon activation by esterases, MGR1 produces superoxide in vitro, an effect that is reversed by superoxide dismutase (SOD). MGR1 produces ROS and increases production of oxidized phosphatidylserine species in HEK293T cells. It reduces viability of HEK293T cells (IC50s = 5.1-6.3 μM).

参考文献
1. Kelkar, D., Ravikumar, G., Mehendale, N., et al. A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase. Nat. Chem. Biol. 15(2), 169-178 (2019).