C21H24N6.2HCl
货号:ajcx19510
CAS:N/A
分子式:C21H24N6.2HCl
分子量:433.4
溶解度:DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
L-Moses is an inhibitor of the p300/CBP-associated factor (PCAF) bromodomain (Kd = 126 nM).1 It is selective for PCAF over GCN5 (Kd = 600 nM) and >4,500-fold selective for PCAF over BRD4. L-Moses displaces the PCAF bromodomain from histone H3.3 in a nanoBRET target engagement assay when used at a concentration of 5 μM.
参考文献
1. Moustakim, M., Clark, P.G.K., Trulli, L., et al. Discovery of a PCAF Bromodomain Chemical Probe. Angew Chem. Int. Ed. Engl. 56(3), 827-831 (2017).