(C2H4O)nC43H83NO10P.Na
货号:ajcx19406
CAS:N/A
分子式:(C2H4O)nC43H83NO10P.Na
分子量：N/A
溶解度:Chloroform: 10 mg/ml,DMF: 2.5mg/mL,DMF:PBS (pH 7.2) (1:1): 0.5mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DSPE-MPEG(2000) is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE;). Formulations containing DSPE-MPEG(2000) have been used in the synthesis of liposomes for the delivery of anticancer and antimalarial agents.1,2,3

参考文献
1. Hasan, G.M., Garg, N., Dogra, E., et al. Inhibition of the growth of Plasmodium falciparum in culture by stearylamine-phosphatidylcholine liposomes. J. Parasitol. Res. 120462 (2011).
2. Rathore, S.S., and Ghosh, P.C. Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: Effect of lysosomotropic agents. Int. J. Pharm. 350(1-2), 79-94 (2008).
3. Haghiralsadat, F., Amoabediny, G., Helder, M.N., et al. A comprehensive mathematical model of drug release kinetics from nano-liposomes, derived from optimization studies of cationic PEGylated liposomal doxorubicin formulations for drug-gene delivery. Artif. Cells Nanomed. Biotechnol. 46(1), 169-177 (2018).