Piperacillin-d5 is intended for use as an internal standard for the quantification of piperacillin by GC- or LC-MS.
货号:ajcx17432
CAS:N/A
分子式:C23H22D5N5O7S
分子量：522.6
溶解度:DMSO: Slightly soluble,Ethanol: Slightly soluble,Methanol: Slightly soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Piperacillin-d5 is intended for use as an internal standard for the quantification of piperacillin by GC- or LC-MS. Piperacillin is a broad-spectrum β-lactam antibiotic of the penicillin class. It is active against Gram-negative and Gram-positive bacteria, including Enterococcus species, E. coli, and P. mirabilis (MIC50s = 0.5-2 µg/ml) as well as gentamicin-susceptible and -resistant strains of P. aeruginosa (MIC50s = 8 and 125 µg/ml, respectively). In a mouse model of systemic infection, piperacillin is active against P. aeruginosa 46220 when used alone or in combination with tazobactam . In the same model, it is less active against P. aeruginosa 46220 DR-2, which contains constitutively active β-lactamase, when used alone than when used in combination with tazobactam (ED50s = >20 and 4.39 mg/animal, respectively). Formulations containing piperacillin in combination with tazobactam have been used in the treatment of moderate-to-severe bacterial infections.