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Thiochrome
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Thiochrome图片
规格:98%
分子量:262.33
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Thiochrome 是硫胺素的天然氧化产物和代谢产物,一种选择性的 M4 受体的乙酰胆碱 (ACh) 亲和力增强剂。Thiochrome 与 Ach 在 M1 至 M3 受体上具有中性协同作用。
货号:ajcx15684
CAS:92-35-3
分子式:C12H14N4OS
分子量:262.33
溶解度:DMSO: 25 mg/mL (95.30 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors[1][2].


Thiochrome can increase the intensity of the reproduction process of the representatives of one-cell organisms worms, crustaceans, insects and fishes[1].

[1]. Petrov SA, et al. Administration of Thiamine and Thiochrome Enhanced Reproduction of Chlorella, Drosophila melanogaster, and Danio. J Nutr Sci Vitaminol (Tokyo). 2016;62(1):6-11. [2]. Lazareno S, et al. Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity. Mol Pharmacol. 2004 Jan;65(1):257-66.