您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Clavulanate lithium
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Clavulanate lithium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Clavulanate lithium图片
规格:98%
分子量:205.09
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Clavulanate lithium 是一种高效的 β-lactamase 抑制剂,可作为抗生素。
货号:ajcx15586
CAS:61177-44-4
分子式:C8H8LiNO5
分子量:205.09
溶解度:H2O: 50 mg/mL (243.80 mM); DMSO: 5 mg/mL (24.38 mM; ultrasonic and warming and heat to 80°C)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].

Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L [2]. Cell Viability Assay[2] Cell Line: L. pneumophila NCTC 1119


[1]. Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11(5): 852-857. [2]. Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23(4):547-56.