Epimagnolin B 是从木兰中分离得到的一种具有抗炎活性的双环氧木质素。Epimagnolin B 抑制 LPS 激活的小胶质细胞中 NO 的产生。Epimagnolin B 具有抗过敏作用。
货号:ajcx15068
CAS:1134188-26-3
分子式:C23H28O7
分子量：416.46
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].

Epimagnolin B exhibits antiallergic effects without affecting the viability of BMMCs[1].

[1]. Kim JY, et al. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40. [2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects.  RSC Advances. July 2017;7(54):34236-34243.