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Rac-GSK547
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rac-GSK547图片
规格:98%
分子量:396.39
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Rac-GSK547 是 GSK547 的消旋体。GSK547 是一种高效的选择性 receptor-interacting serine/threonine protein kinase 1 (RIP1) 抑制剂,可抑制巨噬细胞介导的胰腺癌适应性免疫耐受。
货号:ajcx14102
CAS:N/A
分子式:C20H18F2N6O
分子量:396.39
溶解度:DMSO: ≥ 125 mg/mL (315.35 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Rac-GSK547 is the racemate of GSK547. GSK547 is a highly selective and potent inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIP1), inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer[1].


[1]. Wang W, et al. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer. Cancer Cell. 2018 Nov 12;34(5):757-774.e7.