Dansylglutathione用作一种捕获剂,用于对活性代谢物进行定量和定性分析。
货号:ajcx12362
CAS:75017-02-6
分子式:C22H28N4O8S2
分子量:540.61
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Dansyl glutathione is a trapping agent for the quantitative estimation and identification of reactive metabolites.
Dansyl glutathione is used as a trapping agent to aid the quantitation of adducts following in vitro incubation of drugs with human liver microsomes in the presence and absence of NADPH[1].
[1]. Gan J, et al. In vitro screening of 50 highly prescribed drugs for thiol adduct formation--comparison of potential for drug-induced toxicity and extent of adduct formation. Chem Res Toxicol. 2009 Apr;22(4):690-8.