used for Click chemistry to label alkyne-modified oligonucleotides
货号:ajcx11180
CAS:
分子式:C44H53ClN6O
分子量：717.38
溶解度:≥ 71.7mg/mL in DMSO, ≥ 44.2 mg/mL in EtOH with ultrasonic
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cy3.5 azide is a solid material dye ready for the use in Click Chemistry reaction. Most derivatives of non-sulfonated cyanines have low aqueous solubility except for hydrochlorides of hydrazides and amines. For biomolecule labeling, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.

Cy3.5 azide could easily interfere with a radical polymerisation process as it contains a variety of double bonds. The Cy-3 modified initiator was then used to grow the modified PMPC-PDPA directly from the dye [1].

参考文献:
[1] Gaitzsch, J. ; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055.