JH-XVI-178 是一种高效、选择性的CDK8/19抑制剂，具有低清除率和中等口服药代动力学特性。
货号:ajcx39852
CAS:2648453-53-4
分子式:C22H22ClN7O
分子量：435.91
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties.

[1]. Hatcher JM, et al. Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19. ACS Med Chem Lett. 2021 Oct 22;12(11):1689-1693.