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Cinnamic acid-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cinnamic acid-d6图片
规格:98%
分子量:154.2
包装与价格:
包装价格(元)
100mg电议
250mg电议

产品介绍
Cinnamic acid-d6 (3-Phenylacrylic acid-d6) 是 Cinnamic acid 的氘代物。Cinnamic acid 在癌症干预中有潜在的用途,其对胶质母细胞瘤,黑色素瘤,前列腺癌,肺癌细胞的 IC50 值为 1-4.5 mM。
货号:ajcx39756
CAS:91453-04-2
分子式:C9H2D6O2
分子量:154.2
溶解度:DMSO : 250 mg/mL (1621.27 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Cinnamic acid-d6 (3-Phenylacrylic acid-d6) is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liu L, et al. Cinnamic acid: a natural product with potential use in cancer intervention. Int J Cancer. 1995 Jul 28;62(3):345-50.