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LP99
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LP99图片
CAS NO:1808951-93-0
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍

LP99 (LP-99) is a first-in-class BRD7/9 bromodomain inhibitor (Kd = 99 nM for BRD9) with anti-inflammatoryr activity. It inhibits IL‐6 secretion from THP‐1 cells in a dose‐dependent manner. The effect of LP99 on IL-6 expression demonstrates for the first time that a small-molecule BRD7/9 inhibitor may have a similar function and utility to IL-6 neutralizing antibodies, such as tocilizumab, in the treatment of rheumatoid arthritis.

纯度:≥98%

CAS:1808951-93-0