TCO-PEG4-biotin 是一种 PROTAC linker，属于 PEG 类。TCO-PEG4-biotin 可用于合成一系列 PROTAC 分子。
货号:ajcx37490
CAS:2183440-30-2
分子式:C29H50N4O8S
分子量：614.79
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.