Description: (+)-p-Bromotetramisole Oxalate (also known as (+)-p-Bromotetramisole Oxalate) is a potent, cell-permeable and non-specific alkaline phosphatase inhibitor. In various rat tissues, (-)-p-Bromotetramisole Oxalate (0.1 μM) completely inhibited non-specific alkaline phosphatase. In rat zona glomerulosa, (-)-p-Bromotetramisole Oxalate (100 μM) blocked the inhibition of Na+ pump (Na+, K+-ATPase) induced by angiotensin II. The result suggested that inhibition of the Na+ pump induced by angiotensin II might be mediated by a tyrosine phosphatase.
References: Eur J Pharmacol. 2000 Oct 6;406(1):49-52; Proc Soc Exp Biol Med, 1996, 213(2): 193-195.
纯度:≥98%