Evolocumab (AMG 145) 是一种抑制 PCSK9 的人源化单克隆抗体。Evolocumab 与循环的 PCSK9 蛋白结合，抑制其与 LDLR 结合。Evolocumab 可用于高胆固醇血症和动脉粥样硬化性心血管疾病的研究。
货号:ajcx37310
CAS:1256937-27-5
分子式:N/A
分子量：N/A
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular diseases[1].

[1]. Fala L, et, al. Repatha (Evolocumab): Second PCSK9 Inhibitor Approved by the FDA for Patients with Familial Hypercholesterolemia. Am Health Drug Benefits. 2016 Mar;9(Spec Feature):136-9.