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(+)-Coclaurine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(+)-Coclaurine hydrochloride图片
规格:98%
分子量:321.8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride,是一种四氢异喹啉生物碱,从多种植物来源中分离出来,具有抗衰老活性。
货号:ajcx36772
CAS:19894-19-0
分子式:C17H20ClNO3
分子量:321.8
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity[1][2].

An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) hydrochloride produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine hydrochloride blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2].

[1]. [1]Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4(11):e00951.
[2]. H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6.