KRAS G12C inhibitor 15 是一种有效的 KRAS G12C 抑制剂,IC50 为 5 nM,详细信息请参考专利文献 WO2019110751A1 中的化合物 22。
货号:ajcx36530
CAS:2349393-21-9
分子式:C25H21ClF2N4O3
分子量:498.91
溶解度:DMSO : 193.33 mg/mL (387.50 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].
[1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.