Reproxalap (ADX-102) 是一种研究干眼症的活性醛类隔离剂。Reproxalap 与醛 (包括丙二醛和 4-羟基壬醛) 共价结合。
货号:ajcx36358
CAS:916056-79-6
分子式:C12H13ClN2O
分子量：236.7
溶解度:DMSO : 100 mg/mL (422.48 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal[1][2].

[1]. Susan Macdonald, et al. ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain.
[2]. Reproxalap Phase 2b Dry Eye Disease Results.