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4-Formylaminoantipyrine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-Formylaminoantipyrine图片
规格:98%
分子量:231.25
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
4-Formylaminoantipyrine 是氨基苯那酮的排泄代谢物 (metabolite)。Aminophenazone 是一种具有镇痛、抗炎、解热作用的吡唑啉酮。
货号:ajcx34442
CAS:1672-58-8
分子式:C12H13N3O2
分子量:231.25
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1].

[1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther
[2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31.
[3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79.