SHP2-IN-6 hydrochloride 是一种有效的 SHP2 抑制剂,IC50 值为 25.8 nM,详细信息请参见专利 WO2017211303A1,compound 7。
货号:ajcx33984
CAS:2169223-49-6
分子式:C22H27ClF2N6O2S
分子量:513
溶解度:DMSO : 115 mg/mL (224.17 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SHP2-IN-6 hydrochloride is a potent SHP2 inhibitor with an IC50 of 25.8 nM. SHP2-IN-6 hydrochloride is extracted from patent WO2017211303A1, compound 7[1].
SHP2-IN-6 inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM[1].
[1]. Cunbo Ma, et al. Novel heterocyclic derivatives useful as shp2 inhibitors. WO2017211303A1.