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Biotin-NH-PSMA-617
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biotin-NH-PSMA-617图片
规格:98%
分子量:1396.61
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Biotin-NH-PSMA-617 是一种生物素标记的 PSMA-617。PSMA-617 是一种靶向前列腺特异性膜抗原 (PSMA) 的小分子,其直接由肿瘤细胞表达。
货号:ajcx33948
CAS:N/A
分子式:C65H97N13O19S
分子量:1396.61
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Biotin-NH-PSMA-617 is a biotin-tagged PSMA-617. PSMA-617 is a small molecule targeting the prostate-specific membrane antigen (PSMA), which is directly expressed by the tumor cells [1].

PSMA-617 is a PSMA ligand. PSMA-617 shows a significantly improved binding affinity to PSMA as well as a highly efficient internalization into PCa cells. PSMA-617 can be labeled with 68Ga, 177Lu, 111In, and 90Y and, therefore, be used for PET-imaging as well as for radioligand-based therapy[1].

[1]. Kratochwil C, et al. Targeted alpha therapy of mCRPC: Dosimetry estimate of 213Bismuth-PSMA-617. Eur J Nucl Med Mol Imaging. 2018;45(1):31-37. [2]. Afshar-Oromieh A, et al. The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions. J Nucl Med. 2015;56(11):1697-1705.