规格: | 98% |
分子量: | 575.65 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
1g | 电议 |
Background:
Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.