H-D-Phe-Pip-Arg-pNAhydrochloride是一种显色底物，在纤维蛋白原α链的N端部分之后形成，纤维蛋白原是凝血酶的天然底物。H-D-Phe-Pip-Arg-pNAhydrochloride对凝血酶有特异性，用于测定抗凝血酶肝素辅因子(AT-III)。使用H-D-Phe-Pip-Arg-pNAhydrochloride进行的AT-III分析灵敏、准确、易于执行。
货号:ajcx29386
CAS:160192-34-7
分子式:C27H37ClN8O5
分子量：589.09
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform[1][2].

[1]. Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. [2]. van Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.