TAT-GluA2 3Y 是一种干扰肽,通过破坏 AMPAR 的内吞作用来阻断谷氨酸能突触的长期抑制 (LTD)。
货号:ajcx27838
CAS:1404188-93-7
分子式:C115H185N43O29
分子量:2634
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in rats. Also exhibits antinociceptive effects in a rat model of neuropathic pain. Rescues pentobarbital-induced memory retrieval deficits in a rat model of learning and memory.
Wang et al (2018) Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression. Behav.Brain Res. 339 66 PMID:29162383