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3-Methoxycatechol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Methoxycatechol图片
规格:98%
分子量:140.1
包装与价格:
包装价格(元)
5g电议
10g电议
25g电议

产品介绍
A lignan-derived phenol
货号:ajcx26664
CAS:934-00-9
分子式:C7H8O3
分子量:140.1
溶解度:DMF: 3 mg/ml,DMSO: 2 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 2 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

3-Methoxycatechol is a lignan-derived phenol.1It is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50value of 147 µM in a dynamic mass redistribution (DMR) assay using HT-29 cells.2Dietary administration of 3-methoxycatechol (2%) alone, or in a model of multiorgan carcinogenesis induced by nitrosamines, promotes esophageal carcinogenesis in rats.33-Methoxycatechol has been used as a precursor in the enzymatic synthesis of the phenols pyrogallol and purpurogallin and in the electro-organic synthesis of coumestan derivatives.1,4

1.Zhang, S., Xiaofeng, W., and Xiao, Y.Conversion of lignin-derived 3-methoxycatechol to the natural product purpurogallin using bacterial P450 GcoAB and laccase CueOAppl. Microbiol. Biotechnol.106(2)593-603(2022) 2.Deng, H., and Fang, Y.The three tatecholics benserazide, catechol and pyrogallol are GPR35 agonistsPharmaceuticals (Basel)6(4)500-509(2013) 3.Hirose, M., Tnaka, H., Takahashi, S., et al.Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis modelCancer Res.53(1)32-37(1993) 4.Golabi, S.M., and Nematollahi, D.Electrochemical study of catechol and some 3-substituted catechols in the prescence of 4-hydroxy coumarin: Application to the electro-organic synthesis of new coumestan derivativesJ. Electroanal. Chem.420(1-2)127-134(1997)