| 规格: | 98% |
| 分子量: | 375.4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
Background:
Rabeprazole sulfone is a metabolite of the proton pump inhibitor rabeprazole .1It is formed from rabeprazole by the cytochrome P450 (CYP) isoform CYP3A. Rabeprazole sulfone has also been found as an impurity in bulk preparations of rabeprazole.2
1.VandenBranden, M., Ring, B.J., Binkley, S.N., et al.Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitorPharmacogenetics6(1)81-91(1996) 2.Reddy, G.M., Bhaskar, B.V., Reddy, P.P., et al.Identification and characterization of potential impurities of rabeprazole sodiumJ. Pharm. Biomed. Anal.43(4)1262-1269(2007)
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