您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Sarafloxacin-d8(hydrochloride)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Sarafloxacin-d8(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sarafloxacin-d8(hydrochloride)图片
规格:98%
分子量:429.9
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
An internal standard for the quantification of sarafloxacin
货号:ajcx25348
CAS:N/A
分子式:C20H9D8F2N3O3·HCl
分子量:429.9
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Sarafloxacin-d8is intended for use as an internal standard for the quantification of sarafloxacin by GC- or LC-MS. Sarafloxacin is a fluoroquinolone antibiotic.1,2It is active against various clinical isolates of bacteria, includingBacteroides, Fusobacterium, Eubacterium, Actinomyces, andPeptococcus(MICs = 0.5-2 µg/ml).1Sarafloxacin inhibitsP. aeruginosaDNA gyrase.3It decreases air sac lesion severity in a chick model ofE. coli-induced colisepticemia when administered at a dose of 8 mg/kg in the drinking water 24 hours per day for five days.2Formulations containing sarafloxacin have previously been used in the treatment of bacterial infections in poultry.


1.Bansal, M.B., and Thadepalli, H.Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitroAntimicrob. Agents Chemother.31(4)619-621(1987) 2.Charleston, B., Gate, J.J., Aitken, I.A., et al.Comparison of the efficacies of three fluoroquinolone antimicrobial agents, given as continuous or pulsed-water medication, against Escherichia coli infection in chickensAntimicrob. Agents Chemother.42(1)83-87(1998) 3.Moir, D.T., Di, M., Opperman, T., et al.A high-throughput, homogeneous, bioluminescent assay for Pseudomonas aeruginosa gyrase inhibitors and other DNA-damaging agentsJ. Biomol. Screen.12(6)855-864(2007)