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PCI 45227
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PCI 45227图片
规格:98%
分子量:474.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An active metabolite of ibrutinib
货号:ajcx24152
CAS:1654820-87-7
分子式:C25H26N6O4
分子量:474.5
溶解度:Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

PCI 45227 is an active metabolite of the Bruton's tyrosine kinase inhibitor ibrutinib .1PCI 45227 is formed from ibrutinib by the cytochrome P450 (CYP) isoform CYP3A.


1.Veeraraghavan, S., Viswanadha, S., Thappali, S., et al.Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI-45227 in rat plasma by LC-MS/MS: Application to a pharmacokinetic studyJ. Pharm. Biomed. Anal.107151-158(2015)